"PKIX path building failed: sun.security.provider.certpath.SunCertPathBuilderException: unable to find valid certification path to requested target" seen when connecting Windchill using Connectors in ThingWorx Platform

<JavaException: com.thingworx.common.exceptions.InvalidRequestException: Unable to Invoke Service : No Integration Runtime Connected>

ERROR c.t.i.r.IntegrationEngine - Exchange process failed with exception thrown : Your route exchange has failed.  Resource Error [PKIX path building failed: sun.security.provider.certpath.SunCertPathBuilderException: unable to find valid certification path to requested target]
java.lang.RuntimeException: Your route exchange has failed.  Resource Error [PKIX path building failed: sun.security.provider.certpath.SunCertPathBuilderException: unable to find valid certification path to requested target]
        at com.twx.integration.route.exceptions.ExceptionHelper.convertToRuntimeException(ExceptionHelper.java:112)
        at com.twx.integration.route.IntegrationEngine.dispatchRoute(IntegrationEngine.java:201)
        at com.twx.integration.client.things.IntegrationRuntimeServer.Invoke(IntegrationRuntimeServer.java:72)
        at java.base/jdk.internal.reflect.NativeMethodAccessorImpl.invoke0(Native Method)
        at java.base/jdk.internal.reflect.NativeMethodAccessorImpl.invoke(NativeMethodAccessorImpl.java:62)
        at java.base/jdk.internal.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
        at java.base/java.lang.reflect.Method.invoke(Method.java:566)
        at com.thingworx.common.processors.ReflectionProcessor.processService(ReflectionProcessor.java:230)
        at com.thingworx.communications.client.things.VirtualThing.invokeService(VirtualThing.java:1126)
        at com.thingworx.communications.client.things.VirtualThing.handleServiceRequest(VirtualThing.java:1034)
        at com.thingworx.communications.client.ConnectedThingClient.handleRequest(ConnectedThingClient.java:315)
        at com.thingworx.communications.client.processor.ClientProcessorTask.run(ClientProcessorTask.java:55)
        at java.base/java.util.concurrent.Executors$RunnableAdapter.call(Executors.java:515)
        at java.base/java.util.concurrent.FutureTask.run(FutureTask.java:264)
        at java.base/java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1128)
        at java.base/java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:628)
        at java.base/java.lang.Thread.run(Thread.java:829)