"java.net.NoRouteToHostException: No route to host (Host unreachable)" error in Windchill

• java.net.NoRouteToHostException: No route to host (Host unreachable) error during Windchill startup or in Server Status page
• Mount vault folder on replica server with SSL/HTTPS protocol failed with error

ERROR [ajp-nio-127.0.0.1-8010-exec-1] wt.util.jmx.WDSJMXConnector Administrator - Error connecting to WindchillDS JMX
java.io.IOException: Failed to retrieve RMIServer stub: javax.naming.CommunicationException [Root exception is java.rmi.ConnectIOException: Exception creating connection to: CorporateLdap.domain.com; nested exception is: 
    java.net.NoRouteToHostException: No route to host (Host unreachable)]
    at javax.management.remote.rmi.RMIConnector.connect(RMIConnector.java:369)

• FlexPLM server down and BGMS log contains error below:

INFO  [main] wt.system.err  - javax.naming.CommunicationException: ADHostname.domain.com:3268 [Root exception is java.net.NoRouteToHostException: No route to host (Host unreachable)]
date/time INFO  [main] wt.system.err  -     at com.sun.jndi.ldap.Connection.<init>(Connection.java:238)
date/time INFO  [main] wt.system.err  -     at com.sun.jndi.ldap.LdapClient.<init>(LdapClient.java:137)
date/time INFO  [main] wt.system.err  -     at com.sun.jndi.ldap.LdapClient.getInstance(LdapClient.java:1609)
date/time INFO  [main] wt.system.err  -     at com.sun.jndi.ldap.LdapCtx.connect(LdapCtx.java:2749)

date/time INFO  [main] wt.system.err  - Caused by: java.net.NoRouteToHostException: No route to host (Host unreachable)
date/time  INFO  [main] wt.system.err  -     at java.net.PlainSocketImpl.socketConnect(Native Method)

date/time  INFO  [main] wt.system.err  - wt.org.OrganizationServicesIEException: javax.naming.CommunicationException: ADHostname.domain.com:3268
date/time INFO  [main] wt.system.err  -     at wt.org.LdapServices.queryPrincipalsFromLdap(LdapServices.java:955)

date/time FATAL [main] wt.method.server  - MethodServerMain abort
wt.util.WTException: wt.org.OrganizationServicesIEException: javax.naming.CommunicationException: ADHostname.domain.com:3268

date/time ERROR [wt.log4j.jmx.AsyncJDBCAppender.worker-3] wt.log4j.jmx.AsyncJDBCAppender  - Exception while flushing connection: default
java.sql.SQLRecoverableException: IO Error: Socket read interrupted

date/time ERROR [wt.log4j.jmx.AsyncJDBCAppender.worker-3] wt.log4j.jmx.AsyncJDBCAppender  - MiscLogEvents: exception raised closing prepared statement
java.sql.SQLRecoverableException: Closed Connection
    at oracle.jdbc.driver.PhysicalConnection.needLine(PhysicalConnection.java:3247)

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• Windchill Loader failed while installing, with below error message in MethodServer log:

Caused by: java.rmi.ConnectIOException: Exception creating connection to: <hostname>; nested exception is: 
    java.net.NoRouteToHostException: No route to host  (Host unreachable)
    at java.rmi/sun.rmi.transport.tcp.TCPEndpoint.newSocket(TCPEndpoint.java:635)
    at java.rmi/sun.rmi.transport.tcp.TCPChannel.createConnection(TCPChannel.java:209)
    at java.rmi/sun.rmi.transport.tcp.TCPChannel.newConnection(TCPChannel.java:196)
    at java.rmi/sun.rmi.server.UnicastRef.invoke(UnicastRef.java:132)
    at wt.cache.CacheManager_Stub.registerSlave(Unknown Source)
    at wt.cache.RemoteCacheServer.registerSlaveInternal(RemoteCacheServer.java:197)
    ... 22 more
Caused by: java.net.NoRouteToHostException: No route to host  (Host unreachable)
    at java.base/java.net.PlainSocketImpl.socketConnect(Native Method)
    at java.base/java.net.AbstractPlainSocketImpl.doConnect(AbstractPlainSocketImpl.java:412)
    at java.base/java.net.AbstractPlainSocketImpl.connectToAddress(AbstractPlainSocketImpl.java:255)
    at java.base/java.net.AbstractPlainSocketImpl.connect(AbstractPlainSocketImpl.java:237)
    at java.base/java.net.SocksSocketImpl.connect(SocksSocketImpl.java:392)
    at java.base/java.net.Socket.connect(Socket.java:609)
    at java.base/java.net.Socket.connect(Socket.java:558)
    at java.base/java.net.Socket.<init>(Socket.java:454)
    at java.base/java.net.Socket.<init>(Socket.java:231)
    at java.rmi/sun.rmi.transport.tcp.TCPDirectSocketFactory.createSocket(TCPDirectSocketFactory.java:40)
    at java.rmi/sun.rmi.transport.tcp.TCPEndpoint.newSocket(TCPEndpoint.java:617)

• Getting error while adding Active Directory user to multiple groups
• NotificationQueue is in Ready state and not moving in Executing state
• Error in BackgroundMethod Server logs 

  wt.notify.NotificationException: wt.org.OrganizationServicesIEException: javax.naming.CommunicationException: <AD Hostname:port>:3269
  
  Nested exception is: wt.org.OrganizationServicesIEException: javax.naming.CommunicationException: <AD Hostname:port>:3269
  
                 at wt.org.LdapServices.queryPrincipalsFromLdap(LdapServices.java:1148)
  
                 at wt.org.LdapServices.queryPrincipals(LdapServices.java:2511)
  
                 at jdk.internal.reflect.GeneratedMethodAccessor1048.invoke(Unknown Source)
  
                 at java.base/jdk.internal.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
  
                 at java.base/java.lang.reflect.Method.invoke(Method.java:566)
  
                 at wt.services.ServiceFactory$ServerInvocationHandler.invoke(ServiceFactory.java:399)
  
                 at com.sun.proxy.$Proxy74.queryPrincipals(Unknown Source)
  
                 at wt.adapter.delegate.LdapServiceDelegate.queryPrincipals(LdapServiceDelegate.java:188)
  
                 at wt.org.StandardOrganizationServicesManager._queryPrincipals(StandardOrganizationServicesManager.java:12263)
  
                 at wt.org.StandardOrganizationServicesManager._queryPrincipals(StandardOrganizationServicesManager.java:12216)
  
                 at wt.org.StandardOrganizationServicesManager._queryPrincipals(StandardOrganizationServicesManager.java:12201)
  
                 at wt.org.StandardOrganizationServicesManager.findLikeUsers(StandardOrganizationServicesManager.java:4106)
  
                 at wt.org.StandardOrganizationServicesManager.findLikeUsers(StandardOrganizationServicesManager.java:4131)
  
                 at jdk.internal.reflect.GeneratedMethodAccessor1139.invoke(Unknown Source)
  
                 at java.base/jdk.internal.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
  
                 at java.base/java.lang.reflect.Method.invoke(Method.java:566)
  
                 at wt.services.ServiceFactory$ServerInvocationHandler.invoke(ServiceFactory.java:399)
  
                 at com.sun.proxy.$Proxy73.findLikeUsers(Unknown Source)
  
                 at wt.notify.TemplateEmailNotification.send(TemplateEmailNotification.java:608)
  
                 at wt.notify.StandardNotificationManager.processSend(StandardNotificationManager.java:2990)
  
                 at jdk.internal.reflect.GeneratedMethodAccessor606.invoke(Unknown Source)
  
                 at java.base/jdk.internal.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
  
                 at java.base/java.lang.reflect.Method.invoke(Method.java:566)
  
                 at wt.queue.QueueEntry.execute(QueueEntry.java:231)
  
                 at wt.queue.ProcessingQueue.execEntry(ProcessingQueue.java:312)
  
                 at wt.queue.ProcessingQueue.execEntries(ProcessingQueue.java:898)
  
                 at wt.queue.PollingQueueThread.run(PollingQueueThread.java:103)